According to Lu imatinib
1-((3r)-3-(4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo(3,4-d)pyrimidin-1-yl)-1-piperidinyl)-2-propen-1-one
CAS: 936563-96-1
Molecular Formula: C25H24N6O2
According to Lu imatinib - Names and Identifiers
According to Lu imatinib - Physico-chemical Properties
| Molecular Formula | C25H24N6O2 |
| Molar Mass | 440.5 |
| Density | 1.34 |
| Melting Point | 153-158°C |
| Boling Point | 715.0±60.0 °C(Predicted) |
| Flash Point | 386.2±32.9 °C |
| Solubility | Soluble in DMSO ( up to at least 25 mg/ml) |
| Appearance | solid |
| Color | White or off-white |
| pKa | 4.09±0.30(Predicted) |
| Storage Condition | -20°C |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
According to Lu imatinib - Introduction
Ibrutinib (PCI-32765) is an effective and highly selective Btk inhibitor. IC50 is 0.5 nM. It acts on Bmx, CSK, FGR, BRK and HCK. It is moderately effective and has slightly weaker effects on EGFR, Yes, ErbB2, JAK3.
Last Update：2022-10-16 17:30:16
According to Lu imatinib - Introduction
1-((3r)-3-(4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo(3,4-d)pyrimidin-1-yl)-1-piperidinyl)-2-propen-1-one is a chemical substance, the following is about the substance's properties, use, preparation and safety information:
Nature:
-Appearance: Usually a white crystalline solid.
-Molecular formula: C23H20N6O
-Molecular weight: 396.44g/mol
-Melting point: about 210-220°C
-Solubility: Soluble in common organic solvents, such as ethanol and chloroform.
Use:
- 1-((3r)-3-(4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo(3,4-d)pyrimidin-1-yl)-1-piperidinyl)-2-propen-1-one is an anti-tumor drug. As an inhibitor, it can inhibit the proliferation of tumor cells by regulating apoptosis and cell cycle.
Preparation Method:
The preparation method of 1-((3r)-3-(4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo(3,4-d)pyrimidin-1-yl)-1-piperidinyl)-2-propen-1-one is relatively complicated and not easy to describe. In general, it can be obtained by a multi-step synthesis method. Specific synthetic routes may be optimized and adjusted as needed.
Safety Information:
- 1-((3r)-3-(4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo(3,4-d)pyrimidin-1-yl)-1-piperidinyl)-2-propen-1-one is a chemical substance, so you need to pay attention to safety when using and handling.
-The substance may pose a potential risk to health and the environment. When in use, wear appropriate protective equipment, such as gloves and glasses, to avoid contact with the skin and eyes.
-When storing, keep it in a dry, cool and ventilated place, away from fire and other flammable materials.
-Follow local environmental regulations when disposing of waste and treat it as hazardous waste.
-Detailed safety information and operating instructions can be found in the product safety data sheet (MSDS). It is recommended to read carefully and follow the corresponding safety operating specifications before use.
Nature:
-Appearance: Usually a white crystalline solid.
-Molecular formula: C23H20N6O
-Molecular weight: 396.44g/mol
-Melting point: about 210-220°C
-Solubility: Soluble in common organic solvents, such as ethanol and chloroform.
Use:
- 1-((3r)-3-(4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo(3,4-d)pyrimidin-1-yl)-1-piperidinyl)-2-propen-1-one is an anti-tumor drug. As an inhibitor, it can inhibit the proliferation of tumor cells by regulating apoptosis and cell cycle.
Preparation Method:
The preparation method of 1-((3r)-3-(4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo(3,4-d)pyrimidin-1-yl)-1-piperidinyl)-2-propen-1-one is relatively complicated and not easy to describe. In general, it can be obtained by a multi-step synthesis method. Specific synthetic routes may be optimized and adjusted as needed.
Safety Information:
- 1-((3r)-3-(4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo(3,4-d)pyrimidin-1-yl)-1-piperidinyl)-2-propen-1-one is a chemical substance, so you need to pay attention to safety when using and handling.
-The substance may pose a potential risk to health and the environment. When in use, wear appropriate protective equipment, such as gloves and glasses, to avoid contact with the skin and eyes.
-When storing, keep it in a dry, cool and ventilated place, away from fire and other flammable materials.
-Follow local environmental regulations when disposing of waste and treat it as hazardous waste.
-Detailed safety information and operating instructions can be found in the product safety data sheet (MSDS). It is recommended to read carefully and follow the corresponding safety operating specifications before use.
Last Update：2024-04-09 19:04:56
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Tel: +86-17551318830
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Product Name: 1-((3r)-3-(4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo(3,4-d)pyrimidin-1-yl)-1-piperidinyl)-2-propen-1-one Request for quotation
CAS: 936563-96-1
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 936563-96-1
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Multiple SpecificationsSpot supply
Product Name: Ibrutinib Visit Supplier Webpage Request for quotationCAS: 936563-96-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple SpecificationsSpot supply
Product Name: Ibrutinib (PCI-32765) Visit Supplier Webpage Request for quotationCAS: 936563-96-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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